科研之友
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摘要
objective: to compare serum retinol levels in preschool children during an episode of pneumonia and 45 days after the resolution of the infection. methods: the study was conducted with preschool children without any infection (control group, n = 9) or children hospitalized for pneumonia (n = 12), who were evaluated soon after hospitalization (phase 1) and 45 days later (phase 2). nutritional assessment included anthropometric measurements, a food questionnaire, and laboratory blood routine examination, including urinary and serum retinol levels. paired student t or mann-whitney tests were used as required. results: food intake was similar between groups. blood hemoglobin and serum sodium and albumin decreased during phase 1, while there were higher c-reactive protein serum values. urinary retinol levels remained unchanged whereas serum retinol increased significantly after pneumonia recovery. conclusions: during the course of pneumonia, children had transient decrease in serum levels of vitamin a, an epiphenomenon of the acute phase response.
