Circulating tumor DNA in NK/T and peripheral T cell lymphoma ☆

作者：Huo, Yu-Jia; Zhao, Wei-Li^*

来源：Seminars in Hematology, 2023, 60(3): 173-177.

DOI：10.1053/j.seminhematol.2023.07.003

• ctDNA
• NK/T cell lymphoma
• Peripheral T-cell lymphoma
• Prognosis
• Treatment response
• Surveillance

Natural killer (NK)/T-cell lymphomas (NK/TCL) and peripheral T-cell lymphomas (PTCL) are aggressive hematological malignancies. With the development of next-generation sequencing, circulating tumor DNA (ctDNA) can be detected by several techniques with clinical implications. So far, the effect of ctDNA in pretreatment prognosis prediction, longitudinal monitoring of treatment response and surveillance of long-term remission or relapse in NK/TCL and PTCL has been reported in several researches.

• 单位
  上海市闵行区中心医院; 医学基因组学国家重点实验室; 上海交通大学