Enantioselective Oxidative (4+3) Cycloadditions between Allenamides and Furans through Bifunctional Hydrogen‐Bonding/Ion‐Pairing Interactions

作者：Laura Villar; Dr Uxue Uria; Dr Jose I Martínez; Dr Liher Prieto; Dr Efraim Reyes; Dr Luisa Carrillo; Prof Dr Jose L Vicario

来源：Angewandte Chemie, 2017, 129(35): 10671-10674.

DOI：10.1002/ange.201704804

• Asymmetrische Katalyse
• Cycloadditionen
• Ionenpaarkatalyse
• Organokatalyse
• Sauerstoffheterocyclen

Abstract(#br)BINOL‐based N‐trifluoromethanesulfonyl phosphoramides catalyze the enantioselective (4+3) cycloaddition between furans and oxyallyl cations, the latter being generated in situ by oxidation of allenamides. The chiral organic phosphoramide counteranion is proposed to engage in the activat...