科研之友
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摘要
acne fulminans (af) is a rare disorder, the most severe form of the entire clinical spectrum of acne. it is characterized by emergence of painful inflammatory nodules that turn into ulcers, concomitant with systemic manifestations. it can be induced by isotretinoin and some authors believe that the occurrence of this condition is dose dependent. the treatment is controversial and there is no consensus up to this time. a case of this rare disease, developed during use of isotretinoin in low doses, is presented.
