内吗啡肽-2的人工合成及其酶促降解

作者：李俊; 陈钧辉; 聂永军; 王新昌

来源：中国生物化学与分子生物学报, 2004, (02): 270-274.

DOI：10.13865/j.cnki.cjbmb.2004.02.026

• endomorphin 2
• solution phase synthesis
• proteolysis
• brain synaptic membrane endomorphin 2
• brain synaptic membrane

The recently discovered native endomorphin 2 plays an important role in opioid analgesia, but its metabolic fate in the organism remains relatively little known. The successful synthesis of endomorphin 2 was carried out by solution method. The C teminal dipeptide and the N terminal dipeptide h...

• 单位
  南京大学; 医药生物技术国家重点实验室