科研之友
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摘要
Ultraviolet (UV), as an efficient and green disinfection technology, has been widely applied to inactivate the pathogens in air, water, and surface. Recently, far UV-C radiation (200-230 nm) has drawn great attention, as it is harmless to human within the normal dose range for disinfection, which has great potential to conduct in situ disinfection with human presence.An overview on far UV-C light sources, inactivation mechanisms, and human health and safety to far UV-C exposure was provided in this article. It was found that krypton-chloride (KrCl) excimer lamps with a main peak at 222 nm and half-peak width at 4 nm were the most mature far UV-C light sources for disinfection, far UV-C inactivated pathogenic microorganisms through protein damage and nucleic acid interfere,and the inactivation ability of far UV-C was stronger than that of traditional UV-C (such as 254 nm). No adverse health effects such as erythema and photokeratitis had been reported for far UV-C irradiation within the dose range required by regular disinfection. However, high dose of far UV-C radiation should still be used with caution in practical applications, where the maximum safe dose should be determined based on experimental evidence and increased gradually. Meanwhile, the use of far-UV-C in collaboration with ventilation system or ozone quenching system should be considered to avoid secondary damage caused by associated ozone. Overall, this article will provide reference for efficient and secure application of far UV-C in disinfection and control of highly infectious epidemics.
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