Research Progress of Vaccines in the Treatment of Lung Cancer [疫苗在肺癌治疗中的研究进展]

作者：Chen R.-B.; Chen T.^*

来源：中国全科医学, 2018, 21(23): 2777-2780.

DOI：10.3969/j.issn.1007-9572.2018.00.145

• Cancer vaccines
• Carcinoma,non-small-cell lung
• Lung neoplasms

Lung cancer is the most common malignant tumor in the world with high incidence and mortality.As the most common type of lung cancer,non-small cell lung cancer accounts for 80%-85% of it.At present,the treatment of lung cancer is surgical treatment combined with radiotherapy and chemotherapy.However,surgical treatment is mainly applicable to stage Ⅰ,Ⅱ,and specific stage ⅢA non-small cell lung cancer,while its 5-year overall survival rate is less than 50%.Therefore,it is extremely urgent to find safer and more effective treatments.With the research of immunological mechanism of tumors,immunotherapy has been advocated and the main methods are immunosuppressants,vaccine therapy,which induces specific anti-tumor immunity against specific tumor-associated antigens.This article mainly reviews the vaccine treatment of lung cancer.

• 单位
  三峡大学