摘要

<正>1文献来源Oxnard GR, Arcila ME, Sima CS, et al. Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: Distinct natural history of patients with tumors harboring the T790M mutation [J]. Clin Cancer Res, 2011,17(6):1616-1622. 2证据水平