脓毒症免疫抑制与耐药菌产生的关系

作者:Gengxin Cai; Jingkun Ye; Miaoyun Wen*
来源:中华危重病急救医学, 2018, 30(11): 1095-1098.
DOI:10.3760/CMA.J.ISSN.2095-4352.2018.011.017

摘要

Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection. Immunosuppression is an important factor of secondary infection in the late state of sepsis,including multi-drugs resistant bacteria, which ultimately leads to the death of patients. The aim of this article was to help clinical staffs better manage patients with sepsis, improve long-term survival rate of the patients, and reduce their re-hospitalization rate by reviewing the relationship between sepsis-induced immunosuppression and multi-drugs resistant bacteria through three aspects: the mechanism of sepsis-induced immunosuppression, the mechanism of antibiotic resistance and the relationship between sepsis-induced immunosuppression and secondary infections. ? 2018 Heilongjiang Institute of Science and Technology Information.

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